Entity Details

Primary name IL27RA
Entity type gene
Source Source Link

Details

PrimaryID9466
RefseqGene
SymbolIL27RA
Nameinterleukin 27 receptor subunit alpha
Chromosome19
Location19p13.12
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-04-13
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsI27RA_HUMAN

GO terms

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GOName
GO:0002827 positive regulation of T-helper 1 type immune response
GO:0002829 negative regulation of type 2 immune response
GO:0004888 transmembrane signaling receptor activity
GO:0004896 cytokine receptor activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006955 immune response
GO:0007166 cell surface receptor signaling pathway
GO:0009897 external side of plasma membrane
GO:0019221 cytokine-mediated signaling pathway
GO:0019955 cytokine binding
GO:0032700 negative regulation of interleukin-17 production
GO:0032715 negative regulation of interleukin-6 production
GO:0032720 negative regulation of tumor necrosis factor production
GO:0032729 positive regulation of interferon-gamma production
GO:0042022 interleukin-12 receptor complex
GO:0042104 positive regulation of activated T cell proliferation
GO:0043235 receptor complex
GO:0045509 interleukin-27 receptor activity
GO:0048302 regulation of isotype switching to IgG isotypes
GO:0050830 defense response to Gram-positive bacterium
GO:0070106 interleukin-27-mediated signaling pathway
GO:0070757 interleukin-35-mediated signaling pathway
GO:0072536 interleukin-23 receptor complex
GO:2000317 negative regulation of T-helper 17 type immune response
GO:2000408 negative regulation of T cell extravasation

Diseases

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Interactions

40 interactions

InteractorPartnerSourcesPublicationsLink
IL27RABRICD5BioGRID, IntAct32296183 details
IL27RADEFB121BioGRID, IntAct32296183 details
IL27RAYIPF6BioGRID, IntAct32296183 details
IL27RAGALNT15BioGRID, IntAct32296183 details
IL27RASLC41A2BioGRID, IntAct32296183 details
IL27RAMFSD5BioGRID, IntAct32296183 details
IL27RADERL3BioGRID, IntAct32296183 details
IL27RACLDN2BioGRID, IntAct32296183 details
IL27RASTAT1BioGRID, HPRD12734330 details
IL27RAJAK1BioGRID12734330 details
IL27RAEBI3BioGRID, HPRD12121660 details
IL27RAIL27BioGRID, HPRD12121660 details
IL27RAMAPK8HPRD12734330 details
IL27RATMEM30BBioGRID, IntAct28514442 details
IL27RALRP11BioGRID, IntAct28514442 details
IL27RARHBDD3BioGRID, IntAct28514442 details
IL27RAFNDC3ABioGRID, IntAct28514442 details
IL27RACELSR2BioGRID, IntAct28514442 details
IL27RADNAJC18BioGRID, IntAct28514442 details
IL27RATMX1BioGRID, IntAct28514442 details
IL27RATMX4BioGRID, IntAct28514442 details
IL27RAULBP3BioGRID, IntAct28514442 details
IL27RANDC1BioGRID, IntAct28514442 details
IL27RALENG8BioGRID, IntAct28514442 details
IL27RAGLMNBioGRID, IntAct28514442 details
IL27RAPLD6BioGRID, IntAct28514442 details
IL27RAPOTEEBioGRID, IntAct28514442 details
IL27RADEPDC1BioGRID, IntAct28514442 details
IL27RAGNB2BioGRID, IntAct28514442 details
IL27RATNFSF9BioGRID, IntAct28514442 details
IL27RACANXBioGRID, IntAct28514442 details
IL27RAB4GALT1BioGRID, IntAct28514442 details
IL27RAFGFR1BioGRID, IntAct28514442 details
IL27RAHLA-AIntAct28514442 details
IL27RACOX1BioGRID, IntAct28514442 details
IL27RAAP1G2BioGRID, IntAct28514442 details
IL27RAB4GALT5BioGRID, IntAct28514442 details
IL27RAPLXNB2BioGRID, IntAct28514442 details
IL27RANRP1BioGRID, IntAct28514442 details
IL27RASRPRABioGRID, IntAct28514442 details