Entity Details

Primary name PTGES
Entity type gene
Source Source Link

Details

PrimaryID9536
RefseqGene
SymbolPTGES
Nameprostaglandin E synthase
Chromosome9
Location9q34.11
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-08-11
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPTGES_HUMAN

GO terms

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GOName
GO:0001516 prostaglandin biosynthetic process
GO:0002526 acute inflammatory response
GO:0002544 chronic inflammatory response
GO:0004364 glutathione transferase activity
GO:0004602 glutathione peroxidase activity
GO:0004667 prostaglandin-D synthase activity
GO:0005641 nuclear envelope lumen
GO:0005789 endoplasmic reticulum membrane
GO:0006693 prostaglandin metabolic process
GO:0007165 signal transduction
GO:0008285 negative regulation of cell population proliferation
GO:0014070 response to organic cyclic compound
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0019233 sensory perception of pain
GO:0019371 cyclooxygenase pathway
GO:0031620 regulation of fever generation
GO:0032308 positive regulation of prostaglandin secretion
GO:0032496 response to lipopolysaccharide
GO:0032526 response to retinoic acid
GO:0034097 response to cytokine
GO:0043295 glutathione binding
GO:0048471 perinuclear region of cytoplasm
GO:0050220 prostaglandin-E synthase activity
GO:0050727 regulation of inflammatory response
GO:0051592 response to calcium ion

Diseases

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Interactions

22 interactions

InteractorPartnerSourcesPublicationsLink
PTGESTMEM222BioGRID, IntAct32296183 details
PTGESPLP2BioGRID, IntAct32296183 details
PTGESSMCO4BioGRID, IntAct32296183 details
PTGESSEC22ABioGRID, IntAct32296183 details
PTGESTMEM65BioGRID, IntAct32296183 details
PTGESGIMAP5BioGRID, IntAct32296183 details
PTGESSERP2BioGRID, IntAct32296183 details
PTGESYIF1ABioGRID, IntAct32296183 details
PTGESEHHADHBioGRID, IntAct32296183 details
PTGESVAPBBioGRID, IntAct32296183 details
PTGESGIMAP1BioGRID, IntAct32296183 details
PTGESBET1BioGRID, IntAct32296183 details
PTGESVAMP4BioGRID, IntAct32296183 details
PTGESTMEM19BioGRID, IntAct32296183 details
PTGESVAMP3BioGRID, IntAct32296183 details
PTGESC4orf3BioGRID, IntAct32296183 details
PTGESPTGESBioGRID18682561 20369883 21797823 details
PTGESUSP9XBioGRID31285948 details
PTGESPTGER1HPRD8253813 details
PTGESPTGER2HPRD8163486 details
PTGESGOLT1BBioGRID, IntAct26496610 details
PTGESCFTRBioGRID26618866 details