Entity Details

Primary name I17RC_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8NAC3
EntryNameI17RC_HUMAN
FullNameInterleukin-17 receptor C
TaxID9606
Evidenceevidence at protein level
Length791
SequenceStatuscomplete
DateCreated2005-06-21
DateModified2021-06-02

Ontological Relatives

GenesIL17RC

GO terms

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GOName
GO:0005102 signaling receptor binding
GO:0005886 plasma membrane
GO:0006954 inflammatory response
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0030368 interleukin-17 receptor activity
GO:0032755 positive regulation of interleukin-6 production
GO:0050832 defense response to fungus
GO:0071621 granulocyte chemotaxis
GO:0097400 interleukin-17-mediated signaling pathway
GO:1900017 positive regulation of cytokine production involved in inflammatory response

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR013568 SEFIR domainDomainDomain
IPR027841 Interleukin-17 receptor C/E, N-terminalDomainDomain
IPR039465 Interleukin-17 receptor-likeFamilyFamily

Diseases

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Disease IDSourceNameDescription
616445 OMIMCandidiasis, familial, 9 (CANDF9)A disorder characterized by altered immune responses and impaired clearance of fungal infections, selective against Candida. It is characterized by persistent and/or recurrent infections of the skin, nails and mucous membranes caused by organisms of the genus Candida, mainly Candida albicans. The disease is caused by variants affecting the gene represented in this entry.

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
I17RC_HUMANCIKS_HUMANBioGRID24120361 details