Entity Details

Primary name NT5C_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8TCD5
EntryNameNT5C_HUMAN
FullName5'(3')-deoxyribonucleotidase, cytosolic type
TaxID9606
Evidenceevidence at protein level
Length201
SequenceStatuscomplete
DateCreated2003-10-31
DateModified2021-06-02

Ontological Relatives

GenesNT5C

GO terms

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GOName
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006195 purine nucleotide catabolic process
GO:0006204 IMP catabolic process
GO:0006249 dCMP catabolic process
GO:0008252 nucleotidase activity
GO:0008253 5'-nucleotidase activity
GO:0009223 pyrimidine deoxyribonucleotide catabolic process
GO:0016311 dephosphorylation
GO:0019103 pyrimidine nucleotide binding
GO:0042802 identical protein binding
GO:0046050 UMP catabolic process
GO:0046055 dGMP catabolic process
GO:0046074 dTMP catabolic process
GO:0046079 dUMP catabolic process
GO:0046135 pyrimidine nucleoside catabolic process
GO:0046872 metal ion binding
GO:0050483 IMP 5'-nucleotidase activity
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR010708 5'(3')-deoxyribonucleotidaseFamilyFamily
IPR023214 HAD superfamilyFamilyHomologous superfamily
IPR036412 HAD-like superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00709 LamivudineDrugbanksmall molecule

Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
NT5C_HUMANTNS2_HUMANBioGRID, IntAct25814554 details
NT5C_HUMANNT5C_HUMANBioGRID, HPRD, IntAct2833155 31515488 32296183 details
NT5C_HUMANDISC1_HUMANIntAct31413325 details