Entity Details

Primary name RPAC1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO15160
EntryNameRPAC1_HUMAN
FullNameDNA-directed RNA polymerases I and III subunit RPAC1
TaxID9606
Evidenceevidence at protein level
Length346
SequenceStatuscomplete
DateCreated1998-12-15
DateModified2021-06-02

Ontological Relatives

GenesPOLR1C

GO terms

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GOName
GO:0001054 RNA polymerase I activity
GO:0001056 RNA polymerase III activity
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0005654 nucleoplasm
GO:0005666 RNA polymerase III complex
GO:0005736 RNA polymerase I complex
GO:0005829 cytosol
GO:0006360 transcription by RNA polymerase I
GO:0006361 transcription initiation from RNA polymerase I promoter
GO:0006363 termination of RNA polymerase I transcription
GO:0032481 positive regulation of type I interferon production
GO:0045815 positive regulation of gene expression, epigenetic
GO:0046983 protein dimerization activity

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001514 DNA-directed RNA polymerase, 30-40kDa subunit, conserved siteSiteConserved site
IPR011262 DNA-directed RNA polymerase, insert domainDomainDomain
IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-typeDomainDomain
IPR033901 DNA-directed RNA polymerases I and III subunit AC40FamilyFamily
IPR036603 RNA polymerase, RBP11-like subunitFamilyHomologous superfamily
IPR036643 DNA-directed RNA polymerase, insert domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

128 interactions

InteractorPartnerSourcesPublicationsLink
RPAC1_HUMANNDKA_HUMANBioGRID, HPRD, IntAct16189514 21988832 25416956 31515488 32296183 details
RPAC1_HUMANRPAC2_HUMANBioGRID, HPRD, IntAct16189514 21988832 24981860 25416956 26344197 28514442 32296183 8955128 details
RPAC1_HUMANRPA49_HUMANBioGRID, HPRD, IntAct15226435 17353931 24981860 28514442 9254723 details
RPAC1_HUMANMYD88_HUMANBioGRID, IntAct21988832 details
RPAC1_HUMANCLUS_HUMANBioGRID, IntAct21988832 details
RPAC1_HUMANMYO5B_HUMANBioGRID, IntAct21988832 details
RPAC1_HUMANRPB11_HUMANBioGRID, IntAct21988832 24981860 25416956 28514442 32296183 details
RPAC1_HUMANTARA_HUMANBioGRID, IntAct21988832 details
RPAC1_HUMANBACD2_HUMANBioGRID, IntAct21988832 25416956 32296183 details
RPAC1_HUMANTRI27_HUMANBioGRID, IntAct25416956 32296183 details
RPAC1_HUMANKCTD1_HUMANBioGRID, IntAct25416956 32296183 details
RPAC1_HUMANCOR1B_HUMANBioGRID, IntAct21988832 details
RPAC1_HUMANVIME_HUMANBioGRID, IntAct21988832 details
RPAC1_HUMANSAXO1_HUMANBioGRID, IntAct25416956 details
RPAC1_HUMANCOR1A_HUMANBioGRID, IntAct21988832 details
RPAC1_HUMANSMN_HUMANBioGRID, IntAct25416956 32296183 details
RPAC1_HUMANTASO2_HUMANBioGRID, IntAct25416956 details
RPAC1_HUMANK1C19_HUMANBioGRID, IntAct25416956 details
RPAC1_HUMANIHO1_HUMANBioGRID, IntAct25416956 details
RPAC1_HUMANRIM3A_HUMANBioGRID, IntAct25416956 32296183 details
RPAC1_HUMANITF2_HUMANBioGRID, IntAct25416956 details
RPAC1_HUMANATRIP_HUMANBioGRID, IntAct25416956 details
RPAC1_HUMANIKZF3_HUMANBioGRID, IntAct25416956 27107012 31515488 32296183 details
RPAC1_HUMANBIRC7_HUMANBioGRID, IntAct25416956 32296183 details
RPAC1_HUMANT22D4_HUMANBioGRID, IntAct25416956 32296183 details
RPAC1_HUMANP2R3C_HUMANBioGRID, IntAct25416956 details
RPAC1_HUMANMBIP1_HUMANBioGRID, IntAct25416956 details
RPAC1_HUMANCBY2_HUMANBioGRID, IntAct27107012 32296183 details
RPAC1_HUMANLZTS2_HUMANBioGRID, IntAct25416956 details
RPAC1_HUMANTRI14_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANTFP11_HUMANBioGRID, IntAct27107012 32296183 details
RPAC1_HUMANLNX2_HUMANBioGRID, IntAct27107012 details
RPAC1_HUMANK2C75_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANNEDD4_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANNIF3L_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANMKRN3_HUMANBioGRID, IntAct27107012 32296183 details
RPAC1_HUMANGO45_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANLZTS1_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANGRPE1_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANKR122_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANFOXR2_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANHDX_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANUNKL_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANZIM2_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANSTMN3_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANBHLH9_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANXPA_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANZBT42_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANSPC1L_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANCGBP1_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANARHG5_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANVINEX_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANBIN3_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANTM121_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANSPY1_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANZN554_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANRPB1C_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANK22O_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANLRIF1_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANRUSC1_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANZFP57_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANHXD12_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANZRAN1_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANZBED1_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANMORN3_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANTRAIP_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANTAXB1_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANTNNI1_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANNDKM_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANPSA1_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANBACD1_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANCBX8_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANUBP54_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANNDUBA_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANTEX43_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANKRA31_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANZN835_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANGMPPB_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANRBM48_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANGOG6A_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANHNRH1_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANATL4_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANGG6L9_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANCA105_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANEFC4B_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANEFHC2_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANZN688_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANZN655_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANDRC4_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANAVPI1_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANCCNK_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANGSTO2_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANCD045_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANTLE5_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANMEI4_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANTCPG_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANRT23_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANRSP14_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANRPA34_HUMANBioGRID, IntAct15226435 24981860 28514442 details
RPAC1_HUMANKLF15_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANPIHD2_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANCRYA2_HUMANIntAct32814053 details
RPAC1_HUMANHXB9_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANRPC22_HUMANBioGRID16189514 21988832 24981860 25416956 26344197 28514442 32296183 8955128 details
RPAC1_HUMANINCA1_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANPDIP3_HUMANBioGRID32296183 details
RPAC1_HUMANCCD33_HUMANBioGRID25416956 32296183 details
RPAC1_HUMANFUMH_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANMEOX2_HUMANBioGRID32296183 details
RPAC1_HUMANRPB7_HUMANBioGRID, IntAct24981860 32296183 details
RPAC1_HUMANRPB1B_HUMANBioGRID32296183 details
RPAC1_HUMANZN547_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANFMR1_HUMANBioGRID32296183 details
RPAC1_HUMANEP400_HUMANBioGRID32296183 details
RPAC1_HUMANCU058_HUMANBioGRID32296183 details
RPAC1_HUMANRIM3C_HUMANBioGRID32296183 details
RPAC1_HUMANWASH1_HUMANBioGRID32296183 details
RPAC1_HUMANZC21C_HUMANBioGRID, IntAct32296183 details
RPAC1_HUMANYPEL3_HUMANBioGRID32296183 details
RPAC1_HUMANPHLA3_HUMANIntAct17353931 details
RPAC1_HUMANIKBB_HUMANHPRD, IntAct14743216 details
RPAC1_HUMANCIAO1_HUMANIntAct17353931 details
RPAC1_HUMANRPC4_HUMANBioGRID, IntAct12391170 24981860 26186194 26344197 28514442 details
RPAC1_HUMANGSTK1_HUMANIntAct17353931 details
RPAC1_HUMANWRN_HUMANBioGRID, HPRD11971179 details
RPAC1_HUMANFLNA_HUMANDIP22307607 details
RPAC1_HUMANPMS1_HUMANBioGRID17148452 details
RPAC1_HUMANFGF11_HUMANBioGRID28027390 details