Entity Details

Primary name FZD8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9H461
EntryNameFZD8_HUMAN
FullNameFrizzled-8
TaxID9606
Evidenceevidence at protein level
Length694
SequenceStatuscomplete
DateCreated2001-12-05
DateModified2021-06-02

Ontological Relatives

GenesFZD8

GO terms

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GOName
GO:0004930 G protein-coupled receptor activity
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0017147 Wnt-protein binding
GO:0030165 PDZ domain binding
GO:0030182 neuron differentiation
GO:0031625 ubiquitin protein ligase binding
GO:0042813 Wnt-activated receptor activity
GO:0060070 canonical Wnt signaling pathway

Subcellular Location

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Subcellular Location
Cell membrane
Golgi apparatus
Membrane

Domains

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DomainNameCategoryType
IPR000539 Frizzled/Smoothened, transmembrane domainDomainDomain
IPR015526 Frizzled/secreted frizzled-related proteinFamilyFamily
IPR017981 GPCR, family 2-likeDomainDomain
IPR020067 Frizzled domainDomainDomain
IPR036790 Frizzled cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR041776 Frizzled 8, cysteine-rich domainDomainDomain

Diseases

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