Entity Details

Primary name ZBT20_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9HC78
EntryNameZBT20_HUMAN
FullNameZinc finger and BTB domain-containing protein 20
TaxID9606
Evidenceevidence at protein level
Length741
SequenceStatuscomplete
DateCreated2001-09-26
DateModified2021-06-02

Ontological Relatives

GenesZBTB20

GO terms

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GOName
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0016604 nuclear body
GO:0045821 positive regulation of glycolytic process
GO:0046872 metal ion binding
GO:0046889 positive regulation of lipid biosynthetic process
GO:0055088 lipid homeostasis
GO:0071333 cellular response to glucose stimulus
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000210 BTB/POZ domainDomainDomain
IPR011333 SKP1/BTB/POZ domain superfamilyFamilyHomologous superfamily
IPR013087 Zinc finger C2H2-typeDomainDomain
IPR036236 Zinc finger C2H2 superfamilyFamilyHomologous superfamily

Diseases

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Disease IDSourceNameDescription
259050 OMIMPrimrose syndrome (PRIMS)A disease characterized by macrocephaly, intellectual disability, disturbed behavior, dysmorphic facial features, ectopic calcifications, large calcified ear auricles, and progressive muscle wasting. The disease is caused by variants affecting the gene represented in this entry.