Entity Details

Primary name CO9_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP02748
EntryNameCO9_HUMAN
FullNameComplement component C9
TaxID9606
Evidenceevidence at protein level
Length559
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesC9

GO terms

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GOName
GO:0001906 cell killing
GO:0005576 extracellular region
GO:0005579 membrane attack complex
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0006956 complement activation
GO:0006957 complement activation, alternative pathway
GO:0006958 complement activation, classical pathway
GO:0019835 cytolysis
GO:0030449 regulation of complement activation
GO:0044218 other organism cell membrane
GO:0051260 protein homooligomerization
GO:0070062 extracellular exosome
GO:0072562 blood microparticle

Subcellular Location

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Subcellular Location
Secreted
Target cell membrane

Domains

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DomainNameCategoryType
IPR000884 Thrombospondin type-1 (TSP1) repeatRepeatRepeat
IPR001862 Membrane attack complex component/perforin/complement C9FamilyFamily
IPR002172 Low-density lipoprotein (LDL) receptor class A repeatRepeatRepeat
IPR009030 Growth factor receptor cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR020863 Membrane attack complex component/perforin domain, conserved siteSiteConserved site
IPR020864 Membrane attack complex component/perforin (MACPF) domainDomainDomain
IPR023415 Low-density lipoprotein (LDL) receptor class A, conserved siteSiteConserved site
IPR036055 LDL receptor-like superfamilyFamilyHomologous superfamily
IPR036383 Thrombospondin type-1 (TSP1) repeat superfamilyFamilyHomologous superfamily
IPR037567 Complement component C9FamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB09130 CopperDrugbanksmall molecule

Interactions

5 interactions