Entity Details
| Primary name |
CALCB_HUMAN |
| Entity type |
UniProt |
| Source |
Source Link |
Details
| Accession | P10092 |
| EntryName | CALCB_HUMAN |
| FullName | Calcitonin gene-related peptide 2 |
| TaxID | 9606 |
| Evidence | evidence at protein level |
| Length | 127 |
| SequenceStatus | complete |
| DateCreated | 1989-07-01 |
| DateModified | 2021-06-02 |
GO terms
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| GO | Name |
| GO:0002862 | negative regulation of inflammatory response to antigenic stimulus |
| GO:0005184 | neuropeptide hormone activity |
| GO:0005576 | extracellular region |
| GO:0005615 | extracellular space |
| GO:0006874 | cellular calcium ion homeostasis |
| GO:0007165 | signal transduction |
| GO:0007186 | G protein-coupled receptor signaling pathway |
| GO:0007189 | adenylate cyclase-activating G protein-coupled receptor signaling pathway |
| GO:0031716 | calcitonin receptor binding |
| GO:0051480 | regulation of cytosolic calcium ion concentration |
Subcellular Location
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| Subcellular Location |
| Secreted |
Domains
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| Domain | Name | Category | Type |
| IPR001693 | Calcitonin peptide-like | Domain | Domain |
| IPR015476 | Calcitonin gene-related peptide | Family | Family |
| IPR018360 | Calcitonin, conserved site | Site | Conserved site |
| IPR021116 | Calcitonin/adrenomedullin | Family | Family |
| IPR021117 | Calcitonin-like | Family | Family |
Drugs
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| Drug | Name | Source | Type |
| DB12228 | Telcagepant | Drugbank | small molecule |
| DB14040 | Eptinezumab | Drugbank | biotech |
| DB14041 | Fremanezumab | Drugbank | biotech |
| DB14042 | Galcanezumab | Drugbank | biotech |
Interactions
1 interaction