Entity Details

Primary name FA5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP12259
EntryNameFA5_HUMAN
FullNameCoagulation factor V
TaxID9606
Evidenceevidence at protein level
Length2224
SequenceStatuscomplete
DateCreated1989-10-01
DateModified2021-06-02

Ontological Relatives

GenesF5

GO terms

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GOName
GO:0002576 platelet degranulation
GO:0005507 copper ion binding
GO:0005576 extracellular region
GO:0005788 endoplasmic reticulum lumen
GO:0005886 plasma membrane
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0007596 blood coagulation
GO:0008015 blood circulation
GO:0016020 membrane
GO:0030134 COPII-coated ER to Golgi transport vesicle
GO:0031091 platelet alpha granule
GO:0031093 platelet alpha granule lumen
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane
GO:0043687 post-translational protein modification
GO:0044267 cellular protein metabolic process
GO:0048208 COPII vesicle coating
GO:1903561 extracellular vesicle

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000421 Coagulation factor 5/8 C-terminal domainDomainDomain
IPR008972 CupredoxinFamilyHomologous superfamily
IPR008979 Galactose-binding-like domain superfamilyFamilyHomologous superfamily
IPR009271 Coagulation factor V, LSPDRepeatRepeat
IPR011707 Multicopper oxidase, N-termianlDomainDomain
IPR024715 Coagulation factor 5/8-likeFamilyFamily
IPR033138 Multicopper oxidases, conserved siteSiteConserved site

Diseases

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Drugs

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DrugNameSourceType
DB00055 Drotrecogin alfaDrugbankbiotech
DB05777 Thrombomodulin AlfaDrugbankbiotech
DB09130 CopperDrugbanksmall molecule
DB11300 ThrombinDrugbankbiotech
DB11312 Protein CDrugbankbiotech
DB11571 Human thrombinDrugbankbiotech
DB11572 Thrombin alfaDrugbankbiotech
DB13149 Protein S humanDrugbankbiotech
DB13151 Anti-inhibitor coagulant complexDrugbankbiotech