Entity Details

Primary name T2FB_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP13984
EntryNameT2FB_HUMAN
FullNameGeneral transcription factor IIF subunit 2
TaxID9606
Evidenceevidence at protein level
Length249
SequenceStatuscomplete
DateCreated1990-01-01
DateModified2021-06-02

Ontological Relatives

GenesGTF2F2

GO terms

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GOName
GO:0000398 mRNA splicing, via spliceosome
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005674 transcription factor TFIIF complex
GO:0006366 transcription by RNA polymerase II
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0006368 transcription elongation from RNA polymerase II promoter
GO:0006370 7-methylguanosine mRNA capping
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0015630 microtubule cytoskeleton
GO:0016070 RNA metabolic process
GO:0016251 RNA polymerase II general transcription initiation factor activity
GO:0016787 hydrolase activity
GO:0042795 snRNA transcription by RNA polymerase II
GO:0050434 positive regulation of viral transcription
GO:0097550 transcription preinitiation complex

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR003196 Transcription initiation factor IIF, beta subunitFamilyFamily
IPR011039 Transcription Factor IIF, Rap30/Rap74, interactionFamilyHomologous superfamily
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily
IPR040450 TFIIF beta subunit, HTH domainDomainDomain
IPR040504 TFIIF, beta subunit, N-terminalDomainDomain

Diseases

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Interactions

58 interactions

InteractorPartnerSourcesPublicationsLink
T2FB_HUMANTF2B_HUMANBioGRID, HPRD, MINT16878124 26344197 8662660 details
T2FB_HUMANT2FA_HUMANBioGRID, DIP, HPRD, IntAct, MINT11183778 24981860 26344197 30415952 31467278 7827505 7854423 8441635 8662660 details
T2FB_HUMANHMGA1_HUMANBioGRID, IntAct18850631 details
T2FB_HUMANRMP_HUMANHPRD, IntAct, UniProt12737519 20195357 details
T2FB_HUMANRL27A_HUMANBioGRID, IntAct20195357 details
T2FB_HUMANDYT2B_HUMANBioGRID, IntAct20195357 details
T2FB_HUMANMARE3_HUMANBioGRID, IntAct32296183 details
T2FB_HUMANFHL2_HUMANBioGRID, IntAct32296183 details
T2FB_HUMANZMY19_HUMANBioGRID, IntAct32296183 details
T2FB_HUMANRPAB1_HUMANBioGRID, DIP, HPRD11278533 26344197 27193682 details
T2FB_HUMANT2EA_HUMANBioGRID, HPRD11113176 25492609 7926747 details
T2FB_HUMANTBP_HUMANBioGRID, HPRD8577725 details
T2FB_HUMANAHR_HUMANBioGRID, HPRD8794892 details
T2FB_HUMANARNT_HUMANBioGRID, HPRD8794892 details
T2FB_HUMANFOS_HUMANBioGRID, HPRD8628277 details
T2FB_HUMANJUN_HUMANBioGRID, HPRD8628277 details
T2FB_HUMANMSX2_HUMANBioGRID, HPRD9265625 details
T2FB_HUMANATF4_HUMANBioGRID, HPRD9295363 details
T2FB_HUMANTCEA1_HUMANBioGRID9305922 details
T2FB_HUMANT2EB_HUMANBioGRID, HPRD11113176 9677423 details
T2FB_HUMANANDR_HUMANBioGRID, HPRD9238003 details
T2FB_HUMANKLF5_HUMANBioGRID, HPRD9089417 details
T2FB_HUMANMYC_HUMANBioGRID30415952 details
T2FB_HUMANYETS4_HUMANBioGRID20618999 details
T2FB_HUMANUBXN8_HUMANIntAct20195357 details
T2FB_HUMANA4_HUMANIntAct20195357 details
T2FB_HUMANCOX6C_HUMANIntAct20195357 details
T2FB_HUMANTRFE_HUMANIntAct20195357 details
T2FB_HUMANSTK38_HUMANIntAct20195357 details
T2FB_HUMANVAV3_HUMANIntAct20195357 details
T2FB_HUMANPIPNA_HUMANIntAct20195357 details
T2FB_HUMANAT1A1_HUMANIntAct20195357 details
T2FB_HUMANNP1L1_HUMANIntAct20195357 details
T2FB_HUMANCSTN1_HUMANIntAct20195357 details
T2FB_HUMANCRBN_HUMANIntAct20195357 details
T2FB_HUMANZN638_HUMANIntAct20195357 details
T2FB_HUMANACSL3_HUMANIntAct20195357 details
T2FB_HUMANIPO8_HUMANIntAct20195357 details
T2FB_HUMANATG3_HUMANIntAct20195357 details
T2FB_HUMANRN168_HUMANIntAct20195357 details
T2FB_HUMANTASOR_HUMANIntAct20195357 details
T2FB_HUMANMA1A2_HUMANIntAct20195357 details
T2FB_HUMANESF1_HUMANIntAct20195357 details
T2FB_HUMANPFD2_HUMANIntAct20195357 details
T2FB_HUMANCDC23_HUMANIntAct20195357 details
T2FB_HUMANHTSF1_HUMANBioGRID, HPRD10454543 details
T2FB_HUMANRPB1_HUMANBioGRID17643375 26344197 3860504 details
T2FB_HUMANRPB11_HUMANBioGRID15282305 17643375 details
T2FB_HUMANTAF10_HUMANBioGRID10373431 details
T2FB_HUMANTAF5_HUMANBioGRID, HPRD10373431 8758937 details
T2FB_HUMANTAF4_HUMANBioGRID10373431 details
T2FB_HUMANSHLD1_HUMANBioGRID30022168 details
T2FB_HUMANMED1_HUMANBioGRID18391015 details
T2FB_HUMANTRAM2_HUMANHPRD14612417 details
T2FB_HUMANT2FB_HUMANHPRD10523626 details
T2FB_HUMANCREB1_HUMANHPRD8628277 details
T2FB_HUMANATF2_HUMANHPRD8628277 details
T2FB_HUMANCEBPG_HUMANHPRD8628277 details