Entity Details

Primary name AA2BR_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP29275
EntryNameAA2BR_HUMAN
FullNameAdenosine receptor A2b
TaxID9606
Evidenceevidence at protein level
Length332
SequenceStatuscomplete
DateCreated1992-12-01
DateModified2021-06-02

Ontological Relatives

GenesADORA2B

GO terms

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GOName
GO:0000187 obsolete activation of MAPK activity
GO:0001609 G protein-coupled adenosine receptor activity
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006968 cellular defense response
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007190 activation of adenylate cyclase activity
GO:0007254 JNK cascade
GO:0007588 excretion
GO:0044267 cellular protein metabolic process

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR001435 Adenosine A2B receptorFamilyFamily
IPR001634 Adenosine receptorFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00201 CaffeineDrugbanksmall molecule
DB00277 TheophyllineDrugbanksmall molecule
DB00640 AdenosineDrugbanksmall molecule
DB00824 EnprofyllineDrugbanksmall molecule
DB04932 DefibrotideDrugbankbiotech
DB05936 CVT-6883Drugbanksmall molecule