Entity Details

Primary name SYHM_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP49590
EntryNameSYHM_HUMAN
FullNameHistidine--tRNA ligase, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length506
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesHARS2

GO terms

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GOName
GO:0003723 RNA binding
GO:0004821 histidine-tRNA ligase activity
GO:0005524 ATP binding
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005829 cytosol
GO:0006412 translation
GO:0006418 tRNA aminoacylation for protein translation
GO:0006427 histidyl-tRNA aminoacylation
GO:0042802 identical protein binding

Subcellular Location

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Subcellular Location
Mitochondrion

Domains

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DomainNameCategoryType
IPR004154 Anticodon-bindingDomainDomain
IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunitFamilyFamily
IPR006195 Aminoacyl-tRNA synthetase, class IIDomainDomain
IPR015807 Histidine-tRNA ligaseFamilyFamily
IPR033656 Histidyl-anticodon-bindingDomainDomain
IPR036621 Anticodon-binding domain superfamilyFamilyHomologous superfamily
IPR041715 Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domainDomainDomain

Diseases

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Interactions

5 interactions