Entity Details

Primary name CORIN
Entity type gene
Source Source Link

Details

PrimaryID10699
RefseqGeneNG_032679
SymbolCORIN
Namecorin, serine peptidase
Chromosome4
Location4p12
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-07-13
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsCORIN_HUMAN

GO terms

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GOName
GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide
GO:0004175 endopeptidase activity
GO:0004252 serine-type endopeptidase activity
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007565 female pregnancy
GO:0008217 regulation of blood pressure
GO:0009986 cell surface
GO:0015629 actin cytoskeleton
GO:0016021 integral component of membrane
GO:0016486 peptide hormone processing
GO:0016604 nuclear body
GO:0035813 regulation of renal sodium excretion
GO:1903779 regulation of cardiac conduction

Diseases

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Disease IDSourceNameDescription
614595 OMIMPre-eclampsia/eclampsia 5 (PEE5)A hypertensive disorder of pregnancy characterized by new hypertension (blood pressure 140/90 or greater) presenting after 20 weeks' gestation with clinically relevant proteinuria. It impacts 2 individuals, the mother and her child, both of whom can be severely affected. Preeclampsia is one of the causes of maternal mortality and morbidity worldwide. The disease is caused by variants affecting the gene represented in this entry.

Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
CORINAQP6BioGRID, IntAct32296183 details
CORINCLDN5BioGRID, IntAct32296183 details
CORINEMP1BioGRID, IntAct32296183 details
CORINGPX8BioGRID, IntAct32296183 details