Entity Details

Primary name FGF5
Entity type gene
Source Source Link

Details

PrimaryID2250
RefseqGeneNG_029501
SymbolFGF5
Namefibroblast growth factor 5
Chromosome4
Location4q21.21
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1990-06-12
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsFGF5_HUMAN

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0001934 positive regulation of protein phosphorylation
GO:0005104 fibroblast growth factor receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0007267 cell-cell signaling
GO:0007399 nervous system development
GO:0008083 growth factor activity
GO:0008284 positive regulation of cell population proliferation
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0009887 animal organ morphogenesis
GO:0010001 glial cell differentiation
GO:0010628 positive regulation of gene expression
GO:0023019 signal transduction involved in regulation of gene expression
GO:0030154 cell differentiation
GO:0030334 regulation of cell migration
GO:0051781 positive regulation of cell division
GO:0051897 positive regulation of protein kinase B signaling

Diseases

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Disease IDSourceNameDescription
190330 OMIMTrichomegaly (TCMGLY)A morphologic trait characterized by unusually long eyelashes and mild hypertrichosis of eyebrows. It can be observed in association with corneal irritation, cataracts, and hereditary spherocytosis. The disease is caused by variants affecting the gene represented in this entry.

Interactions

7 interactions

InteractorPartnerSourcesPublicationsLink
FGF5FGFR2BioGRID, IntAct18199118 25241761 details
FGF5FGFR1BioGRID, HPRD18199118 8386828 details
FGF5PTX3BioGRID25912421 details
FGF5FGFR4BioGRID, HPRD, IntAct25241761 8663044 details
FGF5FGFR3HPRD8663044 details
FGF5MAPK1BioGRID, IntAct25241761 details
FGF5EGFBioGRID, IntAct25241761 details