Entity Details

Primary name IL27B_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14213
EntryNameIL27B_HUMAN
FullNameInterleukin-27 subunit beta
TaxID9606
Evidenceevidence at protein level
Length229
SequenceStatuscomplete
DateCreated2004-05-24
DateModified2021-06-02

Ontological Relatives

GenesEBI3

GO terms

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GOName
GO:0004896 cytokine receptor activity
GO:0005125 cytokine activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005788 endoplasmic reticulum lumen
GO:0005886 plasma membrane
GO:0006959 humoral immune response
GO:0009897 external side of plasma membrane
GO:0017046 peptide hormone binding
GO:0019221 cytokine-mediated signaling pathway
GO:0019955 cytokine binding
GO:0032729 positive regulation of interferon-gamma production
GO:0033210 leptin-mediated signaling pathway
GO:0042088 T-helper 1 type immune response
GO:0043235 receptor complex
GO:0046641 positive regulation of alpha-beta T cell proliferation
GO:0070106 interleukin-27-mediated signaling pathway
GO:0070757 interleukin-35-mediated signaling pathway

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR003530 Long hematopoietin receptor, soluble alpha chain, conserved siteSiteConserved site
IPR003961 Fibronectin type IIIDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily

Diseases

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