Entity Details

Primary name PTPRR_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ15256
EntryNamePTPRR_HUMAN
FullNameReceptor-type tyrosine-protein phosphatase R
TaxID9606
Evidenceevidence at protein level
Length657
SequenceStatuscomplete
DateCreated2002-11-15
DateModified2021-06-02

Ontological Relatives

GenesPTPRR

GO terms

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GOName
GO:0001701 in utero embryonic development
GO:0004725 protein tyrosine phosphatase activity
GO:0005001 transmembrane receptor protein tyrosine phosphatase activity
GO:0005615 extracellular space
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006470 protein dephosphorylation
GO:0010633 negative regulation of epithelial cell migration
GO:0016021 integral component of membrane
GO:0019901 protein kinase binding
GO:0030054 cell junction
GO:0038128 ERBB2 signaling pathway
GO:0048471 perinuclear region of cytoplasm
GO:0070373 negative regulation of ERK1 and ERK2 cascade

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm

Domains

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DomainNameCategoryType
IPR000242 PTP type protein phosphataseDomainDomain
IPR000387 Tyrosine specific protein phosphatases domainDomainDomain
IPR003595 Protein-tyrosine phosphatase, catalyticDomainDomain
IPR008356 Protein-tyrosine phosphatase, KIM-containingFamilyFamily
IPR016130 Protein-tyrosine phosphatase, active siteSiteActive site
IPR016334 Protein-tyrosine phosphatase, receptor type R/non-receptor type 5FamilyFamily
IPR029021 Protein-tyrosine phosphatase-likeFamilyHomologous superfamily

Diseases

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Interactions

29 interactions

InteractorPartnerSourcesPublicationsLink
PTPRR_HUMANPTPRR_HUMANBioGRID, MINT15978577 27432908 31980649 details
PTPRR_HUMANCADH2_HUMANIntAct19167335 details
PTPRR_HUMANPGFRB_HUMANIntAct19167335 details
PTPRR_HUMANMK14_HUMANBioGRID, DIP, IntAct, MINT10601328 23932588 26186194 27432908 27880917 28514442 details
PTPRR_HUMANMK01_HUMANBioGRID, HPRD, IntAct, MINT10419510 10601328 16148006 25241761 26186194 27880917 28514442 28675297 32296183 9857190 details
PTPRR_HUMANGBRL1_HUMANBioGRID, IntAct32296183 details
PTPRR_HUMANERBB2_HUMANBioGRID, MINT28065597 details
PTPRR_HUMANINSR_HUMANBioGRID, MINT28065597 details
PTPRR_HUMANLMTK2_HUMANBioGRID, MINT28065597 details
PTPRR_HUMANLMTK1_HUMANBioGRID, MINT28065597 details
PTPRR_HUMANERBB4_HUMANBioGRID, MINT28065597 details
PTPRR_HUMANEGFR_HUMANBioGRID, MINT28065597 details
PTPRR_HUMANERBB3_HUMANBioGRID, MINT28065597 details
PTPRR_HUMANTIE2_HUMANBioGRID, MINT28065597 details
PTPRR_HUMANROR1_HUMANBioGRID, MINT28065597 details
PTPRR_HUMANRET_HUMANBioGRID, MINT28065597 details
PTPRR_HUMANRYK_HUMANBioGRID, MINT28065597 details
PTPRR_HUMANROR2_HUMANBioGRID, MINT28065597 details
PTPRR_HUMANIGF1R_HUMANBioGRID, MINT28065597 details
PTPRR_HUMANPTK7_HUMANBioGRID, MINT28065597 details
PTPRR_HUMANEPHA2_HUMANBioGRID, MINT28065597 details
PTPRR_HUMANNTRK1_HUMANBioGRID, MINT25921289 28065597 details
PTPRR_HUMANFGFR2_HUMANBioGRID, MINT28065597 details
PTPRR_HUMANFGFR4_HUMANBioGRID, MINT28065597 details
PTPRR_HUMANVGFR2_HUMANBioGRID, MINT28065597 details
PTPRR_HUMANMK03_HUMANBioGRID, HPRD10066421 10419510 27880917 9857190 details
PTPRR_HUMANMK07_HUMANBioGRID, HPRD12042304 details
PTPRR_HUMANRON_HUMANBioGRID28065597 details
PTPRR_HUMANKAPCA_HUMANHPRD10601328 details