Entity Details

Primary name KS6A2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ15349
EntryNameKS6A2_HUMAN
FullNameRibosomal protein S6 kinase alpha-2
TaxID9606
Evidenceevidence at protein level
Length733
SequenceStatuscomplete
DateCreated1998-12-15
DateModified2021-06-02

Ontological Relatives

GenesRPS6KA2

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0004674 protein serine/threonine kinase activity
GO:0004711 ribosomal protein S6 kinase activity
GO:0004712 protein serine/threonine/tyrosine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0007165 signal transduction
GO:0007268 chemical synaptic transmission
GO:0008285 negative regulation of cell population proliferation
GO:0018105 peptidyl-serine phosphorylation
GO:0035556 intracellular signal transduction
GO:0043065 positive regulation of apoptotic process
GO:0045202 synapse
GO:0045786 negative regulation of cell cycle
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR000961 AGC-kinase, C-terminalDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR016239 Ribosomal protein S6 kinase IIFamilyFamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR017892 Protein kinase, C-terminalDomainDomain
IPR041906 Ribosomal S6 kinase, N-terminal catalytic domainDomainDomain
IPR042766 RSK3, C-terminal catalytic domainDomainDomain

Diseases

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