Entity Details

Primary name CDK10
Entity type gene
Source Source Link

Details

PrimaryID8558
RefseqGene
SymbolCDK10
Namecyclin dependent kinase 10
Chromosome16
Location16q24.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-12-17
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsCDK10_HUMAN

GO terms

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GOName
GO:0004674 protein serine/threonine kinase activity
GO:0004693 cyclin-dependent protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006468 protein phosphorylation
GO:0007089 traversing start control point of mitotic cell cycle
GO:0007346 regulation of mitotic cell cycle
GO:0008285 negative regulation of cell population proliferation
GO:0018107 peptidyl-threonine phosphorylation
GO:0030030 cell projection organization
GO:0032956 regulation of actin cytoskeleton organization
GO:0036064 ciliary basal body
GO:0043410 positive regulation of MAPK cascade
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1902018 negative regulation of cilium assembly

Diseases

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Disease IDSourceNameDescription
617694 OMIMAl Kaissi syndrome (ALKAS)An autosomal recessive developmental disorder characterized by growth retardation, spine malformation, facial dysmorphisms, and developmental delay. The disease is caused by variants affecting the gene represented in this entry.