Entity Details

Primary name NAGS_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8N159
EntryNameNAGS_HUMAN
FullNameN-acetylglutamate synthase, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length534
SequenceStatuscomplete
DateCreated2005-09-13
DateModified2021-06-02

Ontological Relatives

GenesNAGS

GO terms

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GOName
GO:0000050 urea cycle
GO:0004042 acetyl-CoA:L-glutamate N-acetyltransferase activity
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0006526 arginine biosynthetic process
GO:0006536 glutamate metabolic process
GO:0016310 phosphorylation
GO:0034618 arginine binding
GO:0103045 methione N-acyltransferase activity

Subcellular Location

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Subcellular Location
Mitochondrion matrix

Domains

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DomainNameCategoryType
IPR006855 Vertebrate-like NAGS Gcn5-related N-acetyltransferase (GNAT) domainDomainDomain
IPR011243 N-acetylglutamate synthase, animalFamilyFamily
IPR016181 Acyl-CoA N-acyltransferaseFamilyHomologous superfamily
IPR036393 Acetylglutamate kinase-like superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00142 Glutamic acidDrugbanksmall molecule
DB09326 Ammonia N-13Swissprotsmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
NAGS_HUMANTM39B_HUMANHPRD, IntAct16169070 details