Entity Details

Primary name GPBAR_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8TDU6
EntryNameGPBAR_HUMAN
FullNameG-protein coupled bile acid receptor 1
TaxID9606
Evidenceevidence at protein level
Length330
SequenceStatuscomplete
DateCreated2005-12-06
DateModified2021-06-02

Ontological Relatives

GenesGPBAR1

GO terms

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GOName
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0007186 G protein-coupled receptor signaling pathway
GO:0016021 integral component of membrane
GO:0038181 bile acid receptor activity
GO:0038182 G protein-coupled bile acid receptor activity
GO:0038184 cell surface bile acid receptor signaling pathway
GO:0043235 receptor complex
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:1903413 cellular response to bile acid
GO:1904056 positive regulation of cholangiocyte proliferation
GO:2000810 regulation of bicellular tight junction assembly

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB02659 Cholic AcidDrugbanksmall molecule
DB03619 Deoxycholic acidDrugbanksmall molecule
DB06777 Chenodeoxycholic acidDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink