Entity Details

Primary name PTPM1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8WUK0
EntryNamePTPM1_HUMAN
FullNamePhosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
TaxID9606
Evidenceevidence at protein level
Length201
SequenceStatuscomplete
DateCreated2005-08-16
DateModified2021-06-02

Ontological Relatives

GenesPTPMT1

GO terms

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GOName
GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
GO:0004725 protein tyrosine phosphatase activity
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0008138 protein tyrosine/serine/threonine phosphatase activity
GO:0008962 phosphatidylglycerophosphatase activity
GO:0032049 cardiolipin biosynthetic process
GO:0106306 protein serine phosphatase activity
GO:0106307 protein threonine phosphatase activity
GO:2001242 regulation of intrinsic apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Mitochondrion inner membrane

Domains

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DomainNameCategoryType
IPR000387 Tyrosine specific protein phosphatases domainDomainDomain
IPR016130 Protein-tyrosine phosphatase, active siteSiteActive site
IPR020422 Dual specificity protein phosphatase domainDomainDomain
IPR029021 Protein-tyrosine phosphatase-likeFamilyHomologous superfamily
IPR042165 Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1FamilyFamily
IPR044596 Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1-likeFamilyFamily

Diseases

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Interactions

32 interactions

InteractorPartnerSourcesPublicationsLink
PTPM1_HUMANMDFI_HUMANBioGRID, IntAct, MINT21516116 25416956 32296183 details
PTPM1_HUMANTAB1_HUMANBioGRID, MINT21900206 details
PTPM1_HUMANMK06_HUMANBioGRID, MINT21900206 details
PTPM1_HUMANKRA59_HUMANBioGRID, IntAct25416956 32296183 details
PTPM1_HUMANRGS20_HUMANBioGRID, IntAct21516116 25416956 32296183 details
PTPM1_HUMANKRA23_HUMANBioGRID, IntAct25416956 details
PTPM1_HUMANTRI27_HUMANBioGRID, IntAct25416956 details
PTPM1_HUMANKR107_HUMANBioGRID, IntAct25416956 32296183 details
PTPM1_HUMANKR108_HUMANBioGRID, IntAct25416956 32296183 details
PTPM1_HUMANNT2NA_HUMANBioGRID, IntAct25416956 32296183 details
PTPM1_HUMANK1H1_HUMANBioGRID, IntAct25416956 32296183 details
PTPM1_HUMANMTUS2_HUMANBioGRID, IntAct25416956 details
PTPM1_HUMANK1C40_HUMANBioGRID, IntAct25416956 details
PTPM1_HUMANKRA92_HUMANBioGRID, IntAct25416956 32296183 details
PTPM1_HUMANSIAH1_HUMANBioGRID, IntAct25416956 details
PTPM1_HUMANCRTP1_HUMANBioGRID, IntAct32296183 details
PTPM1_HUMANKR123_HUMANBioGRID, IntAct32296183 details
PTPM1_HUMANKRA57_HUMANBioGRID, IntAct32296183 details
PTPM1_HUMANLCE2C_HUMANBioGRID, IntAct32296183 details
PTPM1_HUMANTM14B_HUMANBioGRID, IntAct32296183 details
PTPM1_HUMANGRN_HUMANBioGRID, IntAct32296183 details
PTPM1_HUMANNT2NC_HUMANBioGRID, IntAct25416956 32296183 details
PTPM1_HUMANKR412_HUMANBioGRID, IntAct32296183 details
PTPM1_HUMANKRT34_HUMANBioGRID, IntAct32296183 details
PTPM1_HUMANKRA93_HUMANBioGRID, IntAct32296183 details
PTPM1_HUMANATL4_HUMANBioGRID, IntAct32296183 details
PTPM1_HUMANKRA31_HUMANBioGRID, IntAct32296183 details
PTPM1_HUMANKR109_HUMANBioGRID, IntAct32296183 details
PTPM1_HUMANKRA24_HUMANBioGRID25416956 details
PTPM1_HUMANKR103_HUMANBioGRID25416956 details
PTPM1_HUMANSRB4D_HUMANBioGRID32296183 details
PTPM1_HUMANKRA13_HUMANBioGRID32296183 details