Entity Details

Primary name MIB2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96AX9
EntryNameMIB2_HUMAN
FullNameE3 ubiquitin-protein ligase MIB2
TaxID9606
Evidenceevidence at protein level
Length1013
SequenceStatuscomplete
DateCreated2005-07-05
DateModified2021-06-02

Ontological Relatives

GenesMIB2

GO terms

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GOName
GO:0000151 ubiquitin ligase complex
GO:0000209 protein polyubiquitination
GO:0003779 actin binding
GO:0004842 ubiquitin-protein transferase activity
GO:0005737 cytoplasm
GO:0005769 early endosome
GO:0005829 cytosol
GO:0007219 Notch signaling pathway
GO:0008270 zinc ion binding
GO:0016567 protein ubiquitination
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0061630 ubiquitin protein ligase activity

Subcellular Location

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Subcellular Location
Cytoplasm
Endosome

Domains

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DomainNameCategoryType
IPR000433 Zinc finger, ZZ-typeDomainDomain
IPR001841 Zinc finger, RING-typeDomainDomain
IPR002110 Ankyrin repeatRepeatRepeat
IPR010606 Mib-herc2DomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR020683 Ankyrin repeat-containing domainDomainDomain
IPR036770 Ankyrin repeat-containing domain superfamilyFamilyHomologous superfamily
IPR037252 Mib/herc2 domain superfamilyFamilyHomologous superfamily
IPR040847 Mind bomb, SH3 repeat domainDomainDomain
IPR042056 E3 ubiquitin-protein ligase MIB1/2, zinc finger, ZZ-typeDomainDomain
IPR043145 Zinc finger, ZZ-type superfamilyFamilyHomologous superfamily

Diseases

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