Entity Details

Primary name PKHF1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96S99
EntryNamePKHF1_HUMAN
FullNamePleckstrin homology domain-containing family F member 1
TaxID9606
Evidenceevidence at protein level
Length279
SequenceStatuscomplete
DateCreated2006-10-03
DateModified2021-06-02

Ontological Relatives

GenesPLEKHF1

GO terms

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GOName
GO:0005634 nucleus
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0006915 apoptotic process
GO:0007032 endosome organization
GO:0010008 endosome membrane
GO:0010314 phosphatidylinositol-5-phosphate binding
GO:0010508 positive regulation of autophagy
GO:0016050 vesicle organization
GO:0032266 phosphatidylinositol-3-phosphate binding
GO:0035091 phosphatidylinositol binding
GO:0046872 metal ion binding
GO:0048471 perinuclear region of cytoplasm
GO:0070273 phosphatidylinositol-4-phosphate binding
GO:0072659 protein localization to plasma membrane
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Cytoplasm
Lysosome
Nucleus

Domains

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DomainNameCategoryType
IPR000306 FYVE zinc fingerDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR011011 Zinc finger, FYVE/PHD-typeFamilyHomologous superfamily
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR017455 Zinc finger, FYVE-relatedDomainDomain
IPR037871 Phafin, PH domainDomainDomain
IPR042762 PKHF1, FYVE domainDomainDomain

Diseases

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Interactions

7 interactions