Entity Details

Primary name KCNE5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UJ90
EntryNameKCNE5_HUMAN
FullNamePotassium voltage-gated channel subfamily E regulatory beta subunit 5
TaxID9606
Evidenceevidence at protein level
Length142
SequenceStatuscomplete
DateCreated2002-12-13
DateModified2021-06-02

Ontological Relatives

GenesKCNE5

GO terms

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GOName
GO:0005249 voltage-gated potassium channel activity
GO:0005886 plasma membrane
GO:0008016 regulation of heart contraction
GO:0008076 voltage-gated potassium channel complex
GO:0015459 potassium channel regulator activity
GO:0044325 transmembrane transporter binding
GO:0060048 cardiac muscle contraction
GO:0060306 regulation of membrane repolarization
GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization
GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization
GO:0086005 ventricular cardiac muscle cell action potential
GO:0086011 membrane repolarization during action potential
GO:0086014 atrial cardiac muscle cell action potential
GO:0086091 regulation of heart rate by cardiac conduction
GO:0097623 potassium ion export across plasma membrane
GO:0098915 membrane repolarization during ventricular cardiac muscle cell action potential
GO:1901379 regulation of potassium ion transmembrane transport
GO:1901380 negative regulation of potassium ion transmembrane transport
GO:1901381 positive regulation of potassium ion transmembrane transport
GO:1902260 negative regulation of delayed rectifier potassium channel activity
GO:1903765 negative regulation of potassium ion export across plasma membrane
GO:2001257 regulation of cation channel activity

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR000369 Potassium channel, voltage-dependent, beta subunit, KCNEFamilyFamily

Diseases

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Disease IDSourceNameDescription
300194 OMIMAlport syndrome with mental retardation, midface hypoplasia and elliptocytosis (ATS-MR)An X-linked contiguous gene deletion syndrome characterized by glomerulonephritis, sensorineural hearing loss, mental retardation, midface hypoplasia and elliptocytosis. The gene represented in this entry may be involved in disease pathogenesis.

Drugs

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DrugNameSourceType
DB00228 EnfluraneDrugbanksmall molecule
DB01069 PromethazineDrugbanksmall molecule
DB01110 MiconazoleDrugbanksmall molecule