Entity Details

Primary name SYFA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y285
EntryNameSYFA_HUMAN
FullNamePhenylalanine--tRNA ligase alpha subunit
TaxID9606
Evidenceevidence at protein level
Length508
SequenceStatuscomplete
DateCreated2000-12-08
DateModified2021-06-02

Ontological Relatives

GenesFARSA

GO terms

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GOName
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0004826 phenylalanine-tRNA ligase activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006418 tRNA aminoacylation for protein translation
GO:0006432 phenylalanyl-tRNA aminoacylation
GO:0009328 phenylalanine-tRNA ligase complex
GO:0016020 membrane
GO:0051290 protein heterotetramerization

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR002319 Phenylalanyl-tRNA synthetaseDomainDomain
IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunitFamilyFamily
IPR006195 Aminoacyl-tRNA synthetase, class IIDomainDomain
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily
IPR040586 PheRS DNA binding domain 2DomainDomain
IPR040724 PheRS, DNA binding domain 1DomainDomain
IPR040725 PheRS, DNA binding domain 3DomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00120 PhenylalanineDrugbanksmall molecule