Entity Details

Primary name USH2A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO75445
EntryNameUSH2A_HUMAN
FullNameUsherin
TaxID9606
Evidenceevidence at protein level
Length5202
SequenceStatuscomplete
DateCreated2006-04-04
DateModified2021-06-02

Ontological Relatives

GenesUSH2A

GO terms

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GOName
GO:0001917 photoreceptor inner segment
GO:0002141 stereocilia ankle link
GO:0002142 stereocilia ankle link complex
GO:0005518 collagen binding
GO:0005576 extracellular region
GO:0005604 basement membrane
GO:0005737 cytoplasm
GO:0007601 visual perception
GO:0007605 sensory perception of sound
GO:0009887 animal organ morphogenesis
GO:0009888 tissue development
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0016477 cell migration
GO:0017022 myosin binding
GO:0032391 photoreceptor connecting cilium
GO:0032421 stereocilium bundle
GO:0034446 substrate adhesion-dependent cell spreading
GO:0035315 hair cell differentiation
GO:0036064 ciliary basal body
GO:0042802 identical protein binding
GO:0045184 establishment of protein localization
GO:0045494 photoreceptor cell maintenance
GO:0048496 maintenance of animal organ identity
GO:0050896 response to stimulus
GO:0050953 sensory perception of light stimulus
GO:0060113 inner ear receptor cell differentiation
GO:0060171 stereocilium membrane
GO:1990075 periciliary membrane compartment
GO:1990696 USH2 complex

Subcellular Location

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Subcellular Location
Cell projection
Secreted

Domains

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DomainNameCategoryType
IPR001791 Laminin G domainDomainDomain
IPR002049 Laminin EGF domainDomainDomain
IPR003961 Fibronectin type IIIDomainDomain
IPR006558 LamG-like jellyroll foldDomainDomain
IPR008211 Laminin, N-terminalDomainDomain
IPR013320 Concanavalin A-like lectin/glucanase domain superfamilyFamilyHomologous superfamily
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR026915 UsherinFamilyFamily
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily

Diseases

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Interactions

4 interactions