Entity Details

Primary name TGDS_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95455
EntryNameTGDS_HUMAN
FullNamedTDP-D-glucose 4,6-dehydratase
TaxID9606
Evidenceevidence at protein level
Length350
SequenceStatuscomplete
DateCreated2003-04-23
DateModified2021-06-02

Ontological Relatives

GenesTGDS

GO terms

Show/Hide Table
GOName
GO:0008460 dTDP-glucose 4,6-dehydratase activity
GO:0009225 nucleotide-sugar metabolic process

Subcellular Location

Show/Hide Table

Domains

Show/Hide Table
DomainNameCategoryType
IPR005888 dTDP-glucose 4,6-dehydrataseFamilyFamily
IPR016040 NAD(P)-binding domainDomainDomain
IPR036291 NAD(P)-binding domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table
Disease IDSourceNameDescription
616145 OMIMCatel-Manzke syndrome (CATMANS)A syndrome characterized by Pierre Robin sequence and a unique form of bilateral hyperphalangy causing a clinodactyly of the index finger. Pierre Robin sequence includes an opening in the roof of the mouth (a cleft palate), a large tongue (macroglossia), and a small lower jaw (micrognathia). The disease is caused by variants affecting the gene represented in this entry.

Interactions

3 interactions