Entity Details

Primary name VATB1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP15313
EntryNameVATB1_HUMAN
FullNameV-type proton ATPase subunit B, kidney isoform
TaxID9606
Evidenceevidence at protein level
Length513
SequenceStatuscomplete
DateCreated1990-04-01
DateModified2021-06-02

Ontological Relatives

GenesATP6V1B1

GO terms

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GOName
GO:0001503 ossification
GO:0003091 renal water homeostasis
GO:0003096 renal sodium ion transport
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005902 microvillus
GO:0006693 prostaglandin metabolic process
GO:0006885 regulation of pH
GO:0007588 excretion
GO:0007605 sensory perception of sound
GO:0008286 insulin receptor signaling pathway
GO:0010468 regulation of gene expression
GO:0015078 proton transmembrane transporter activity
GO:0016241 regulation of macroautophagy
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0016328 lateral plasma membrane
GO:0016471 vacuolar proton-transporting V-type ATPase complex
GO:0016787 hydrolase activity
GO:0030534 adult behavior
GO:0033180 proton-transporting V-type ATPase, V1 domain
GO:0033572 transferrin transport
GO:0034198 cellular response to amino acid starvation
GO:0034220 ion transmembrane transport
GO:0035812 renal sodium excretion
GO:0042048 olfactory behavior
GO:0042472 inner ear morphogenesis
GO:0044877 protein-containing complex binding
GO:0045851 pH reduction
GO:0046034 ATP metabolic process
GO:0055064 chloride ion homeostasis
GO:0055074 calcium ion homeostasis
GO:0055075 potassium ion homeostasis
GO:0070062 extracellular exosome
GO:0090383 phagosome acidification
GO:0098850 extrinsic component of synaptic vesicle membrane
GO:1902600 proton transmembrane transport

Subcellular Location

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Subcellular Location
Apical cell membrane
Basolateral cell membrane

Domains

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DomainNameCategoryType
IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domainDomainDomain
IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domainDomainDomain
IPR005723 ATPase, V1 complex, subunit BFamilyFamily
IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active siteSiteActive site
IPR022879 V-type ATP synthase regulatory subunit B/betaFamilyFamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB01133 Tiludronic acidDrugbanksmall molecule

Interactions

76 interactions

InteractorPartnerSourcesPublicationsLink
VATB1_HUMANSUV91_HUMANBioGRID, MINT23455924 details
VATB1_HUMANKDM1A_HUMANBioGRID, MINT23455924 details
VATB1_HUMANHSPB1_HUMANIntAct32814053 details
VATB1_HUMANTTHY_HUMANIntAct32814053 details
VATB1_HUMANWFS1_HUMANIntAct32814053 details
VATB1_HUMANIDLC_HUMANIntAct32814053 details
VATB1_HUMANBAG6_HUMANIntAct32814053 details
VATB1_HUMANKLF11_HUMANIntAct32814053 details
VATB1_HUMANDNJB6_HUMANIntAct32814053 details
VATB1_HUMANKIF1B_HUMANIntAct32814053 details
VATB1_HUMANRNF11_HUMANIntAct32814053 details
VATB1_HUMANATX1_HUMANIntAct32814053 details
VATB1_HUMANTADBP_HUMANIntAct32814053 details
VATB1_HUMANSTX1A_HUMANBioGRID12651853 details
VATB1_HUMANVPP1_HUMANBioGRID, IntAct20541250 21674799 22939629 26186194 28514442 details
VATB1_HUMANVATD_HUMANBioGRID, IntAct21674799 22939629 26186194 28514442 details
VATB1_HUMANVATA_HUMANBioGRID, IntAct21674799 26186194 28514442 details
VATB1_HUMANVATE1_HUMANBioGRID, IntAct21674799 22939629 26186194 28514442 details
VATB1_HUMANVATC1_HUMANBioGRID, IntAct21674799 26186194 28514442 details
VATB1_HUMANVATB2_HUMANBioGRID, IntAct21674799 22939629 26186194 28514442 details
VATB1_HUMANVATG1_HUMANBioGRID, IntAct21674799 26186194 28514442 details
VATB1_HUMANARL8B_HUMANBioGRID21674799 details
VATB1_HUMANVA0D1_HUMANBioGRID21674799 26186194 details
VATB1_HUMANVATH_HUMANBioGRID21674799 details
VATB1_HUMANBAF_HUMANBioGRID21674799 details
VATB1_HUMANLTOR1_HUMANBioGRID21674799 22939629 details
VATB1_HUMANS35F6_HUMANBioGRID21674799 details
VATB1_HUMANCD63_HUMANBioGRID21674799 details
VATB1_HUMANCD9_HUMANBioGRID21674799 details
VATB1_HUMANCHM1A_HUMANBioGRID21674799 details
VATB1_HUMANCHM1B_HUMANBioGRID21674799 details
VATB1_HUMANCHM2B_HUMANBioGRID21674799 details
VATB1_HUMANCHM4B_HUMANBioGRID21674799 details
VATB1_HUMANCHMP5_HUMANBioGRID21674799 details
VATB1_HUMANCATD_HUMANBioGRID21674799 details
VATB1_HUMANDJC13_HUMANBioGRID21674799 details
VATB1_HUMANDNJC5_HUMANBioGRID21674799 details
VATB1_HUMANMYOF_HUMANBioGRID21674799 details
VATB1_HUMANFLOT1_HUMANBioGRID21674799 details
VATB1_HUMANFLOT2_HUMANBioGRID21674799 details
VATB1_HUMANFRIH_HUMANBioGRID21674799 details
VATB1_HUMANGLCM_HUMANBioGRID21674799 details
VATB1_HUMANGGH_HUMANBioGRID21674799 details
VATB1_HUMANGBB1_HUMANBioGRID21674799 details
VATB1_HUMANIST1_HUMANBioGRID21674799 details
VATB1_HUMANLAMP1_HUMANBioGRID21674799 details
VATB1_HUMANLAMP2_HUMANBioGRID21674799 details
VATB1_HUMANMITD1_HUMANBioGRID21674799 details
VATB1_HUMANMYO1B_HUMANBioGRID21674799 details
VATB1_HUMANMYO1D_HUMANBioGRID21674799 details
VATB1_HUMANMYO3B_HUMANBioGRID21674799 details
VATB1_HUMANNICA_HUMANBioGRID21674799 details
VATB1_HUMANPKP4_HUMANBioGRID21674799 details
VATB1_HUMANPLBL1_HUMANBioGRID21674799 details
VATB1_HUMANRB22A_HUMANBioGRID21674799 details
VATB1_HUMANRAB35_HUMANBioGRID21674799 34079125 details
VATB1_HUMANRALB_HUMANBioGRID21674799 details
VATB1_HUMANRRAS_HUMANBioGRID21674799 details
VATB1_HUMANS10AB_HUMANBioGRID21674799 details
VATB1_HUMANSCRB2_HUMANBioGRID21674799 details
VATB1_HUMANAACT_HUMANBioGRID21674799 details
VATB1_HUMANSTOM_HUMANBioGRID21674799 details
VATB1_HUMANSTX12_HUMANBioGRID21674799 details
VATB1_HUMANSTX8_HUMANBioGRID21674799 details
VATB1_HUMANTACD2_HUMANBioGRID21674799 details
VATB1_HUMANTFR1_HUMANBioGRID21674799 details
VATB1_HUMANTM9S1_HUMANBioGRID21674799 details
VATB1_HUMANTM192_HUMANBioGRID21674799 details
VATB1_HUMANTMOD3_HUMANBioGRID21674799 details
VATB1_HUMANVAMP7_HUMANBioGRID21674799 details
VATB1_HUMANVAMP8_HUMANBioGRID21674799 details
VATB1_HUMANCHMP3_HUMANBioGRID21674799 details
VATB1_HUMANVTI1B_HUMANBioGRID21674799 details
VATB1_HUMANVPP4_HUMANBioGRID27127844 details
VATB1_HUMANACTN4_HUMANHPRD10915794 details
VATB1_HUMANNHRF1_HUMANHPRD10748165 details