Entity Details

Primary name ATTY_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP17735
EntryNameATTY_HUMAN
FullNameTyrosine aminotransferase
TaxID9606
Evidenceevidence at protein level
Length454
SequenceStatuscomplete
DateCreated1990-08-01
DateModified2021-06-02

Ontological Relatives

GenesTAT

GO terms

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GOName
GO:0004838 L-tyrosine:2-oxoglutarate aminotransferase activity
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0006103 2-oxoglutarate metabolic process
GO:0006536 glutamate metabolic process
GO:0006559 L-phenylalanine catabolic process
GO:0006572 tyrosine catabolic process
GO:0006979 response to oxidative stress
GO:0009058 biosynthetic process
GO:0016597 amino acid binding
GO:0030170 pyridoxal phosphate binding
GO:0042802 identical protein binding
GO:0046689 response to mercury ion
GO:0051384 response to glucocorticoid

Subcellular Location

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Domains

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DomainNameCategoryType
IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding siteSiteBinding site
IPR004839 Aminotransferase, class I/classIIDomainDomain
IPR005957 Tyrosine aminotransferaseFamilyFamily
IPR005958 Tyrosine/nicotianamine aminotransferaseFamilyFamily
IPR011715 Tyrosine aminotransferase ubiquitination regionDomainDomain
IPR015421 Pyridoxal phosphate-dependent transferase, major domainFamilyHomologous superfamily
IPR015422 Pyridoxal phosphate-dependent transferase, small domainFamilyHomologous superfamily
IPR015424 Pyridoxal phosphate-dependent transferaseFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00114 Pyridoxal phosphateDrugbanksmall molecule
DB00120 PhenylalanineDrugbanksmall molecule
DB00135 TyrosineDrugbanksmall molecule
DB00142 Glutamic acidDrugbanksmall molecule