Entity Details

Primary name DAOA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP59103
EntryNameDAOA_HUMAN
FullNameD-amino acid oxidase activator
TaxID9606
Evidenceevidence at protein level
Length153
SequenceStatuscomplete
DateCreated2002-11-25
DateModified2021-06-02

Ontological Relatives

GenesDAOA

GO terms

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GOName
GO:0005739 mitochondrion
GO:0005794 Golgi apparatus
GO:0008047 enzyme activator activity
GO:0019899 enzyme binding
GO:0043085 positive regulation of catalytic activity
GO:0048471 perinuclear region of cytoplasm
GO:1900758 negative regulation of D-amino-acid oxidase activity

Subcellular Location

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Subcellular Location
Golgi apparatus

Domains

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DomainNameCategoryType
IPR027929 D-amino acid oxidase activatorFamilyFamily

Diseases

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Disease IDSourceNameDescription
181500 OMIMSchizophrenia (SCZD)A complex, multifactorial psychotic disorder or group of disorders characterized by disturbances in the form and content of thought (e.g. delusions, hallucinations), in mood (e.g. inappropriate affect), in sense of self and relationship to the external world (e.g. loss of ego boundaries, withdrawal), and in behavior (e.g bizarre or apparently purposeless behavior). Although it affects emotions, it is distinguished from mood disorders in which such disturbances are primary. Similarly, there may be mild impairment of cognitive function, and it is distinguished from the dementias in which disturbed cognitive function is considered primary. Some patients manifest schizophrenic as well as bipolar disorder symptoms and are often given the diagnosis of schizoaffective disorder. Disease susceptibility may be associated with variants affecting the gene represented in this entry.

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
DAOA_HUMANOXDA_HUMANBioGRID, HPRD12364586 18544534 details
DAOA_HUMANDAOA_HUMANBioGRID18544534 details