Entity Details
Primary name |
NTH_HUMAN |
Entity type |
UniProt |
Source |
Source Link |
Details
Accession | P78549 |
EntryName | NTH_HUMAN |
FullName | Endonuclease III-like protein 1 |
TaxID | 9606 |
Evidence | evidence at protein level |
Length | 312 |
SequenceStatus | complete |
DateCreated | 2003-02-28 |
DateModified | 2021-06-02 |
Subcellular Location
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Subcellular Location |
Mitochondrion |
Nucleus |
Domains
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Domain | Name | Category | Type |
IPR000445 | Helix-hairpin-helix motif | Site | Conserved site |
IPR003265 | HhH-GPD domain | Domain | Domain |
IPR003651 | Endonuclease III-like, iron-sulphur cluster loop motif | Site | Conserved site |
IPR004036 | Endonuclease III-like, conserved site-2 | Site | Conserved site |
IPR011257 | DNA glycosylase | Family | Homologous superfamily |
IPR023170 | Helix-hairpin-helix, base-excision DNA repair, C-terminal | Family | Homologous superfamily |
IPR030841 | Endonuclease III-like protein 1 | Family | Family |
Diseases
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Disease ID | Source | Name | Description |
616415 | OMIM | Familial adenomatous polyposis 3 (FAP3) | A form of familial adenomatous polyposis, a condition characterized by the development of multiple colorectal adenomatous polyps, benign neoplasms derived from glandular epithelium. Some affected individuals may develop colorectal carcinoma. The disease is caused by variants affecting the gene represented in this entry. |
Interactions
5 interactions