Entity Details

Primary name LIPS_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ05469
EntryNameLIPS_HUMAN
FullNameHormone-sensitive lipase
TaxID9606
Evidenceevidence at protein level
Length1076
SequenceStatuscomplete
DateCreated1994-02-01
DateModified2021-06-02

Ontological Relatives

GenesLIPE

GO terms

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GOName
GO:0004771 sterol esterase activity
GO:0004806 triglyceride lipase activity
GO:0005811 lipid droplet
GO:0005829 cytosol
GO:0005901 caveola
GO:0006468 protein phosphorylation
GO:0008203 cholesterol metabolic process
GO:0016020 membrane
GO:0016042 lipid catabolic process
GO:0019433 triglyceride catabolic process
GO:0033878 hormone-sensitive lipase activity
GO:0046340 diacylglycerol catabolic process
GO:0046485 ether lipid metabolic process
GO:0047372 acylglycerol lipase activity
GO:0047376 all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity
GO:0050253 retinyl-palmitate esterase activity
GO:0102258 1,3-diacylglycerol acylhydrolase activity
GO:0102259 1,2-diacylglycerol acylhydrolase activity

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Lipid droplet
Membrane

Domains

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DomainNameCategoryType
IPR002168 Lipase, GDXG, putative histidine active siteSiteActive site
IPR010468 Hormone-sensitive lipase, N-terminalDomainDomain
IPR013094 Alpha/beta hydrolase fold-3DomainDomain
IPR029058 Alpha/Beta hydrolase foldFamilyHomologous superfamily
IPR033140 Lipase, GDXG, putative serine active siteSiteActive site

Diseases

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