Entity Details

Primary name DUS8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ13202
EntryNameDUS8_HUMAN
FullNameDual specificity protein phosphatase 8
TaxID9606
Evidenceevidence at protein level
Length625
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesDUSP8

GO terms

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GOName
GO:0000188 obsolete inactivation of MAPK activity
GO:0004721 phosphoprotein phosphatase activity
GO:0004725 protein tyrosine phosphatase activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006470 protein dephosphorylation
GO:0008330 protein tyrosine/threonine phosphatase activity
GO:0016311 dephosphorylation
GO:0016791 phosphatase activity
GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity
GO:0035335 peptidyl-tyrosine dephosphorylation
GO:0035970 peptidyl-threonine dephosphorylation
GO:0051019 mitogen-activated protein kinase binding
GO:0106306 protein serine phosphatase activity
GO:0106307 protein threonine phosphatase activity

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000387 Tyrosine specific protein phosphatases domainDomainDomain
IPR001763 Rhodanese-like domainDomainDomain
IPR008343 Mitogen-activated protein (MAP) kinase phosphataseFamilyFamily
IPR016130 Protein-tyrosine phosphatase, active siteSiteActive site
IPR020422 Dual specificity protein phosphatase domainDomainDomain
IPR029021 Protein-tyrosine phosphatase-likeFamilyHomologous superfamily
IPR036873 Rhodanese-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
DUS8_HUMANMPIP1_HUMANBioGRID, MINT21900206 details
DUS8_HUMANMK08_HUMANBioGRID, IntAct, MINT21900206 26186194 27432908 27880917 28514442 details