Entity Details

Primary name BCO1
Entity type gene
Source Source Link

Details

PrimaryID53630
RefseqGeneNG_012171
SymbolBCO1
Namebeta-carotene oxygenase 1
Chromosome16
Location16q23.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-03-28
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsBCDO1_HUMAN

GO terms

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GOName
GO:0001523 retinoid metabolic process
GO:0003834 beta-carotene 15,15'-monooxygenase activity
GO:0005829 cytosol
GO:0010436 carotenoid dioxygenase activity
GO:0016121 carotene catabolic process
GO:0035238 vitamin A biosynthetic process
GO:0042572 retinol metabolic process
GO:0042574 retinal metabolic process
GO:0046872 metal ion binding
GO:1901810 beta-carotene metabolic process

Diseases

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Disease IDSourceNameDescription
115300 OMIMHypercarotenemia and vitamin A deficiency, autosomal dominant (HCVAD)A disorder characterized by increased serum beta-carotene, decreased conversion of beta-carotene to vitamin A and decreased serum vitamin A. The disease is caused by variants affecting the gene represented in this entry.

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
BCO1MYCIntAct21150319 details
BCO1ABLIM1BioGRID, IntAct28514442 details