Entity Details

Primary name DAZ4
Entity type gene
Source Source Link

Details

PrimaryID57135
RefseqGene
SymbolDAZ4
Namedeleted in azoospermia 4
ChromosomeY
LocationYq11.23
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-08-29
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsDAZ4_HUMAN

GO terms

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GOName
GO:0003730 mRNA 3'-UTR binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0007275 multicellular organism development
GO:0007283 spermatogenesis
GO:0008494 translation activator activity
GO:0030154 cell differentiation
GO:0032991 protein-containing complex
GO:0045948 positive regulation of translational initiation
GO:0070935 3'-UTR-mediated mRNA stabilization

Diseases

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Disease IDSourceNameDescription
415000 OMIMSpermatogenic failure Y-linked 2 (SPGFY2)A disorder resulting in the absence (azoospermia) or reduction (oligozoospermia) of sperm in the semen, leading to male infertility. The disease may be caused by variants affecting the gene represented in this entry. AZFc deletions in the Yq11.23 region including the DAZ genes are the most common known genetic cause of human male infertility.

Interactions

5 interactions