Entity Details

Primary name HOT_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8IWW8
EntryNameHOT_HUMAN
FullNameHydroxyacid-oxoacid transhydrogenase, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length467
SequenceStatuscomplete
DateCreated2008-03-18
DateModified2021-06-02

Ontological Relatives

GenesADHFE1

GO terms

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GOName
GO:0004022 alcohol dehydrogenase (NAD+) activity
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0006103 2-oxoglutarate metabolic process
GO:0006539 glutamate catabolic process via 2-oxoglutarate
GO:0046872 metal ion binding
GO:0047988 hydroxyacid-oxoacid transhydrogenase activity

Subcellular Location

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Subcellular Location
Mitochondrion

Domains

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DomainNameCategoryType
IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldADomainDomain
IPR039697 Iron-type alcohol dehydrogenase-likeFamilyFamily
IPR042157 Hydroxyacid-oxoacid transhydrogenaseFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB09072 Sodium oxybateSwissprotsmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
HOT_HUMANGNAQ_HUMANBioGRID, IntAct21988832 details
HOT_HUMANLIPC_HUMANBioGRID, IntAct21988832 details