Entity Details

Primary name ADA23_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO75077
EntryNameADA23_HUMAN
FullNameDisintegrin and metalloproteinase domain-containing protein 23
TaxID9606
Evidenceevidence at protein level
Length832
SequenceStatuscomplete
DateCreated2004-12-07
DateModified2021-06-02

Ontological Relatives

GenesADAM23

GO terms

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GOName
GO:0004222 metalloendopeptidase activity
GO:0005178 integrin binding
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007155 cell adhesion
GO:0007417 central nervous system development
GO:0008237 metallopeptidase activity
GO:0098978 glutamatergic synapse
GO:0099056 integral component of presynaptic membrane
GO:1990830 cellular response to leukemia inhibitory factor

Subcellular Location

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Subcellular Location
Cell membrane
Secreted

Domains

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DomainNameCategoryType
IPR000742 EGF-like domainDomainDomain
IPR001590 Peptidase M12B, ADAM/reprolysinDomainDomain
IPR001762 Disintegrin domainDomainDomain
IPR002870 Peptidase M12B, propeptideDomainDomain
IPR006586 ADAM, cysteine-rich domainDomainDomain
IPR024079 Metallopeptidase, catalytic domain superfamilyFamilyHomologous superfamily
IPR034027 Reprolysin domain, adamalysin-typeDomainDomain
IPR036436 Disintegrin domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions