Entity Details

Primary name FZD1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO70421
EntryNameFZD1_MOUSE
FullNameFrizzled-1
TaxID10090
Evidenceevidence at protein level
Length642
SequenceStatuscomplete
DateCreated2001-12-05
DateModified2021-06-02

Ontological Relatives

GenesFzd1

GO terms

Show/Hide Table
GOName
GO:0001934 positive regulation of protein phosphorylation
GO:0003149 membranous septum morphogenesis
GO:0003150 muscular septum morphogenesis
GO:0003151 outflow tract morphogenesis
GO:0004930 G protein-coupled receptor activity
GO:0005102 signaling receptor binding
GO:0005109 frizzled binding
GO:0005886 plasma membrane
GO:0007267 cell-cell signaling
GO:0009986 cell surface
GO:0010976 positive regulation of neuron projection development
GO:0016021 integral component of membrane
GO:0016055 Wnt signaling pathway
GO:0017147 Wnt-protein binding
GO:0030165 PDZ domain binding
GO:0030514 negative regulation of BMP signaling pathway
GO:0030855 epithelial cell differentiation
GO:0035425 autocrine signaling
GO:0036520 astrocyte-dopaminergic neuron signaling
GO:0042493 response to drug
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0042813 Wnt-activated receptor activity
GO:0043005 neuron projection
GO:0044338 canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation
GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046982 protein heterodimerization activity
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0060022 hard palate development
GO:0060070 canonical Wnt signaling pathway
GO:0060412 ventricular septum morphogenesis
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:0090179 planar cell polarity pathway involved in neural tube closure
GO:1903204 negative regulation of oxidative stress-induced neuron death
GO:1905606 regulation of presynapse assembly

Subcellular Location

Show/Hide Table
Subcellular Location
Cell membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR000539 Frizzled/Smoothened, transmembrane domainDomainDomain
IPR015526 Frizzled/secreted frizzled-related proteinFamilyFamily
IPR017981 GPCR, family 2-likeDomainDomain
IPR020067 Frizzled domainDomainDomain
IPR026550 Frizzled-1/2FamilyFamily
IPR036790 Frizzled cysteine-rich domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table