Entity Details

Primary name CHI3L1
Entity type gene
Source Source Link

Details

PrimaryID1116
RefseqGeneNG_013056
SymbolCHI3L1
Namechitinase 3 like 1
Chromosome1
Location1q32.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-01-21
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsCH3L1_HUMAN

GO terms

Show/Hide Table
GOName
GO:0005201 extracellular matrix structural constituent
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005975 carbohydrate metabolic process
GO:0006032 chitin catabolic process
GO:0006915 apoptotic process
GO:0006954 inflammatory response
GO:0007250 activation of NF-kappaB-inducing kinase activity
GO:0008061 chitin binding
GO:0009612 response to mechanical stimulus
GO:0010800 positive regulation of peptidyl-threonine phosphorylation
GO:0030246 carbohydrate binding
GO:0030324 lung development
GO:0031012 extracellular matrix
GO:0032757 positive regulation of interleukin-8 production
GO:0034612 response to tumor necrosis factor
GO:0035580 specific granule lumen
GO:0043312 neutrophil degranulation
GO:0045766 positive regulation of angiogenesis
GO:0048471 perinuclear region of cytoplasm
GO:0051216 cartilage development
GO:0051897 positive regulation of protein kinase B signaling
GO:0070062 extracellular exosome
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0070555 response to interleukin-1
GO:0070741 response to interleukin-6
GO:0071347 cellular response to interleukin-1
GO:0071356 cellular response to tumor necrosis factor

Diseases

Show/Hide Table
Disease IDSourceNameDescription
181500 OMIMSchizophrenia (SCZD)A complex, multifactorial psychotic disorder or group of disorders characterized by disturbances in the form and content of thought (e.g. delusions, hallucinations), in mood (e.g. inappropriate affect), in sense of self and relationship to the external world (e.g. loss of ego boundaries, withdrawal), and in behavior (e.g bizarre or apparently purposeless behavior). Although it affects emotions, it is distinguished from mood disorders in which such disturbances are primary. Similarly, there may be mild impairment of cognitive function, and it is distinguished from the dementias in which disturbed cognitive function is considered primary. Some patients manifest schizophrenic as well as bipolar disorder symptoms and are often given the diagnosis of schizoaffective disorder. Disease susceptibility is associated with variants affecting the gene represented in this entry.
611960 OMIMAsthma-related traits 7 (ASRT7)Asthma-related traits include clinical symptoms of asthma, such as coughing, wheezing, dyspnea, bronchial hyperresponsiveness as assessed by methacholine challenge test, serum IgE levels, atopy and atopic dermatitis. Disease susceptibility is associated with variants affecting the gene represented in this entry.