Entity Details
| Primary name |
SYRM_HUMAN |
| Entity type |
UniProt |
| Source |
Source Link |
Details
| Accession | Q5T160 |
| EntryName | SYRM_HUMAN |
| FullName | Probable arginine--tRNA ligase, mitochondrial |
| TaxID | 9606 |
| Evidence | evidence at protein level |
| Length | 578 |
| SequenceStatus | complete |
| DateCreated | 2006-10-03 |
| DateModified | 2021-06-02 |
Subcellular Location
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| Subcellular Location |
| Mitochondrion matrix |
Domains
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| Domain | Name | Category | Type |
| IPR001278 | Arginine-tRNA ligase | Family | Family |
| IPR001412 | Aminoacyl-tRNA synthetase, class I, conserved site | Site | Conserved site |
| IPR008909 | DALR anticodon binding | Domain | Domain |
| IPR009080 | Aminoacyl-tRNA synthetase, class Ia, anticodon-binding | Family | Homologous superfamily |
| IPR014729 | Rossmann-like alpha/beta/alpha sandwich fold | Family | Homologous superfamily |
| IPR035684 | Arginyl-tRNA synthetase, catalytic core domain | Domain | Domain |
| IPR036695 | Arginyl tRNA synthetase N-terminal domain superfamily | Family | Homologous superfamily |
Diseases
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| Disease ID | Source | Name | Description |
| 611523 | OMIM | Pontocerebellar hypoplasia 6 (PCH6) | A disorder characterized by an abnormally small cerebellum and brainstem, infantile encephalopathy, generalized hypotonia, lethargy and poor feeding. Recurrent apnea, intractable seizures occur early in the course of this condition. The disease is caused by variants affecting the gene represented in this entry. |
Interactions
3 interactions