Entity Details

Primary name NEK10_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6ZWH5
EntryNameNEK10_HUMAN
FullNameSerine/threonine-protein kinase Nek10
TaxID9606
Evidenceevidence at protein level
Length1172
SequenceStatuscomplete
DateCreated2006-11-28
DateModified2021-06-02

Ontological Relatives

GenesNEK10

GO terms

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GOName
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005576 extracellular region
GO:0006468 protein phosphorylation
GO:0031954 positive regulation of protein autophosphorylation
GO:0043406 positive regulation of MAP kinase activity
GO:0046872 metal ion binding
GO:0070372 regulation of ERK1 and ERK2 cascade
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:0120197 mucociliary clearance
GO:1902749 regulation of cell cycle G2/M phase transition
GO:1902911 protein kinase complex

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR008266 Tyrosine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR016024 Armadillo-type foldFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR042666 Serine/threonine-protein kinase Nek10, catalytic domainDomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
NEK10_HUMANHSPB1_HUMANBioGRID, IntAct25277244 details
NEK10_HUMANM3K1_HUMANBioGRID25260751 details