Entity Details

Primary name AK1BF_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionC9JRZ8
EntryNameAK1BF_HUMAN
FullNameAldo-keto reductase family 1 member B15
TaxID9606
Evidenceevidence at protein level
Length316
SequenceStatuscomplete
DateCreated2010-07-13
DateModified2021-06-02

Ontological Relatives

GenesAKR1B15

GO terms

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GOName
GO:0004032 alditol:NADP+ 1-oxidoreductase activity
GO:0004303 estradiol 17-beta-dehydrogenase activity
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005829 cytosol
GO:0006703 estrogen biosynthetic process
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity
GO:0047655 allyl-alcohol dehydrogenase activity
GO:0047834 D-threo-aldose 1-dehydrogenase activity
GO:0047886 farnesol dehydrogenase activity
GO:0052650 NADP-retinol dehydrogenase activity
GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity

Subcellular Location

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Subcellular Location
Cytoplasm
Mitochondrion

Domains

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DomainNameCategoryType
IPR018170 Aldo/keto reductase, conserved siteSiteConserved site
IPR020471 Aldo-keto reductaseFamilyFamily
IPR023210 NADP-dependent oxidoreductase domainDomainDomain
IPR036812 NADP-dependent oxidoreductase domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB06077 LumateperoneDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
AK1BF_HUMANTRAF2_HUMANBioGRID, IntAct32296183 details