Entity Details

Primary name SIAH3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8IW03
EntryNameSIAH3_HUMAN
FullNameSeven in absentia homolog 3
TaxID9606
Evidenceevidence at protein level
Length269
SequenceStatuscomplete
DateCreated2008-05-20
DateModified2021-06-02

Ontological Relatives

GenesSIAH3

GO terms

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GOName
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0007275 multicellular organism development
GO:0031624 ubiquitin conjugating enzyme binding
GO:0031647 regulation of protein stability
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0046872 metal ion binding
GO:0061630 ubiquitin protein ligase activity
GO:1903215 negative regulation of protein targeting to mitochondrion

Subcellular Location

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Subcellular Location
Mitochondrion

Domains

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DomainNameCategoryType
IPR004162 E3 ubiquitin-protein ligase SINA-like, animalFamilyFamily
IPR008974 TRAF-likeFamilyHomologous superfamily
IPR018121 Seven-in-absentia protein, TRAF-like domainDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
SIAH3_HUMANKRA62_HUMANBioGRID, IntAct32296183 details