Entity Details

Primary name DDX60_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8IY21
EntryNameDDX60_HUMAN
FullNameProbable ATP-dependent RNA helicase DDX60
TaxID9606
Evidenceevidence at protein level
Length1712
SequenceStatuscomplete
DateCreated2008-02-05
DateModified2021-06-02

Ontological Relatives

GenesDDX60

GO terms

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GOName
GO:0003690 double-stranded DNA binding
GO:0003724 RNA helicase activity
GO:0003725 double-stranded RNA binding
GO:0003727 single-stranded RNA binding
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0009615 response to virus
GO:0016787 hydrolase activity
GO:0045087 innate immune response
GO:0045111 intermediate filament cytoskeleton
GO:0051607 defense response to virus
GO:1900245 positive regulation of MDA-5 signaling pathway
GO:1900246 positive regulation of RIG-I signaling pathway

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR001650 Helicase, C-terminalDomainDomain
IPR011545 DEAD/DEAH box helicase domainDomainDomain
IPR014001 Helicase superfamily 1/2, ATP-binding domainDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
DDX60_HUMANEIF3E_HUMANBioGRID, IntAct30833792 details