Entity Details

Primary name PTPR2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ92932
EntryNamePTPR2_HUMAN
FullNameReceptor-type tyrosine-protein phosphatase N2
TaxID9606
Evidenceevidence at protein level
Length1015
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesPTPRN2

GO terms

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GOName
GO:0005001 transmembrane receptor protein tyrosine phosphatase activity
GO:0005788 endoplasmic reticulum lumen
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006470 protein dephosphorylation
GO:0006629 lipid metabolic process
GO:0007269 neurotransmitter secretion
GO:0030285 integral component of synaptic vesicle membrane
GO:0030667 secretory granule membrane
GO:0030672 synaptic vesicle membrane
GO:0034260 negative regulation of GTPase activity
GO:0035773 insulin secretion involved in cellular response to glucose stimulus
GO:0043195 terminal bouton
GO:0043235 receptor complex
GO:0043312 neutrophil degranulation
GO:0101003 ficolin-1-rich granule membrane

Subcellular Location

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Subcellular Location
Cytoplasmic vesicle

Domains

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DomainNameCategoryType
IPR000242 PTP type protein phosphataseDomainDomain
IPR000387 Tyrosine specific protein phosphatases domainDomainDomain
IPR003595 Protein-tyrosine phosphatase, catalyticDomainDomain
IPR016130 Protein-tyrosine phosphatase, active siteSiteActive site
IPR021613 Protein-tyrosine phosphatase receptor IA-2 ectodomainDomainDomain
IPR029021 Protein-tyrosine phosphatase-likeFamilyHomologous superfamily
IPR029403 RESP18 domainDomainDomain
IPR033522 Receptor-type tyrosine-protein phosphatase-like N/N2FamilyFamily
IPR038112 Protein-tyrosine phosphatase receptor IA-2, ectodomain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

7 interactions