Entity Details

Primary name AGAP3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96P47
EntryNameAGAP3_HUMAN
FullNameArf-GAP with GTPase, ANK repeat and PH domain-containing protein 3
TaxID9606
Evidenceevidence at protein level
Length875
SequenceStatuscomplete
DateCreated2003-01-27
DateModified2021-06-02

Ontological Relatives

GenesAGAP3

GO terms

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GOName
GO:0003924 GTPase activity
GO:0005096 GTPase activator activity
GO:0005525 GTP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0007165 signal transduction
GO:0016020 membrane
GO:0031593 polyubiquitin modification-dependent protein binding
GO:0034614 cellular response to reactive oxygen species
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043547 positive regulation of GTPase activity
GO:0046872 metal ion binding
GO:0071944 cell periphery

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR001164 Arf GTPase activating proteinDomainDomain
IPR001806 Small GTPaseFamilyFamily
IPR001849 Pleckstrin homology domainDomainDomain
IPR002110 Ankyrin repeatRepeatRepeat
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR020683 Ankyrin repeat-containing domainDomainDomain
IPR020849 Small GTPase, Ras-typeFamilyFamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR036770 Ankyrin repeat-containing domain superfamilyFamilyHomologous superfamily
IPR037278 ARFGAP/RecO-like zinc fingerFamilyHomologous superfamily
IPR038508 ArfGAP domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

4 interactions