Entity Details

Primary name GDF3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NR23
EntryNameGDF3_HUMAN
FullNameGrowth/differentiation factor 3
TaxID9606
Evidenceevidence at protein level
Length364
SequenceStatuscomplete
DateCreated2001-02-21
DateModified2021-06-02

Ontological Relatives

GenesGDF3

GO terms

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GOName
GO:0001501 skeletal system development
GO:0001654 eye development
GO:0005125 cytokine activity
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0008083 growth factor activity
GO:0010453 regulation of cell fate commitment
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0019901 protein kinase binding
GO:0030509 BMP signaling pathway
GO:0030514 negative regulation of BMP signaling pathway
GO:0045600 positive regulation of fat cell differentiation
GO:0045605 negative regulation of epidermal cell differentiation
GO:0060395 SMAD protein signal transduction

Subcellular Location

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Subcellular Location
Cytoplasm
Secreted

Domains

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DomainNameCategoryType
IPR001839 Transforming growth factor-beta, C-terminalDomainDomain
IPR015615 Transforming growth factor-beta-relatedFamilyFamily
IPR017948 Transforming growth factor beta, conserved siteSiteConserved site
IPR029034 Cystine-knot cytokineFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
GDF3_HUMANTDGF1_HUMANBioGRID28126904 details