Entity Details

Primary name PDE8B_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95263
EntryNamePDE8B_HUMAN
FullNameHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B
TaxID9606
Evidenceevidence at protein level
Length885
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesPDE8B

GO terms

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GOName
GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity
GO:0005829 cytosol
GO:0006198 cAMP catabolic process
GO:0007165 signal transduction
GO:0007186 G protein-coupled receptor signaling pathway
GO:0046872 metal ion binding

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000014 PAS domainDomainDomain
IPR002073 3'5'-cyclic nucleotide phosphodiesterase, catalytic domainDomainDomain
IPR003607 HD/PDEase domainDomainDomain
IPR013938 3'5'-cyclic nucleotide phosphodiesterase PDE8DomainDomain
IPR023088 3'5'-cyclic nucleotide phosphodiesteraseFamilyFamily
IPR023174 3'5'-cyclic nucleotide phosphodiesterase, conserved siteSiteConserved site
IPR035965 PAS domain superfamilyFamilyHomologous superfamily
IPR036971 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00201 CaffeineDrugbanksmall molecule
DB09283 TrapidilDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink