Entity Details

Primary name MYH6_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP13533
EntryNameMYH6_HUMAN
FullNameMyosin-6
TaxID9606
Evidenceevidence at transcript level
Length1939
SequenceStatuscomplete
DateCreated1990-01-01
DateModified2021-06-02

Ontological Relatives

GenesMYH6

GO terms

Show/Hide Table
GOName
GO:0000146 microfilament motor activity
GO:0001701 in utero embryonic development
GO:0001725 stress fiber
GO:0002026 regulation of the force of heart contraction
GO:0002027 regulation of heart rate
GO:0005516 calmodulin binding
GO:0005524 ATP binding
GO:0005829 cytosol
GO:0005859 muscle myosin complex
GO:0006936 muscle contraction
GO:0006941 striated muscle contraction
GO:0007512 adult heart development
GO:0007522 visceral muscle development
GO:0008016 regulation of heart contraction
GO:0008217 regulation of blood pressure
GO:0014898 cardiac muscle hypertrophy in response to stress
GO:0016459 myosin complex
GO:0016887 ATP hydrolysis activity
GO:0019901 protein kinase binding
GO:0030016 myofibril
GO:0030017 sarcomere
GO:0030018 Z disc
GO:0030049 muscle filament sliding
GO:0030239 myofibril assembly
GO:0032982 myosin filament
GO:0043462 regulation of ATPase activity
GO:0045214 sarcomere organization
GO:0046034 ATP metabolic process
GO:0051015 actin filament binding
GO:0055009 atrial cardiac muscle tissue morphogenesis
GO:0055010 ventricular cardiac muscle tissue morphogenesis
GO:0060048 cardiac muscle contraction
GO:0060420 regulation of heart growth

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm

Domains

Show/Hide Table
DomainNameCategoryType
IPR000048 IQ motif, EF-hand binding siteSiteBinding site
IPR001609 Myosin head, motor domainDomainDomain
IPR002928 Myosin tailDomainDomain
IPR004009 Myosin, N-terminal, SH3-likeDomainDomain
IPR008989 Myosin S1 fragment, N-terminalFamilyHomologous superfamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR036961 Kinesin motor domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table